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KMID : 1191420120110010053
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Korean Journal of Optometry and Vision Science
2012 Volume.11 No. 1 p.53 ~ p.59
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Risk Factor Analysis of Long-Term Failure of Amniotic Membrane Transplantation for Scleromalacia after Pterygium Excision
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Oh Baek-Lok
Kim Mee-Kum
Choi Hyuk Jin
Wee Won-Ryang
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Abstract
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Purpose: To investigate the risk factors of re-transplantation of amniotic membrane to repair epithelial and scleral defect in scleromalacia after pterygium excision.
Methods: The medical records of fifteen eyes in 14 patients who had followed-up at least 6 months after amniotic membrane transplantation were retrospectively reviewed. We compared presumable risk factors of re-transplantation group (n=4) to those of control group (n=11), such as sex, age, onset of scleromalacia after pterygium excision, activity of scleritis at the time of operation, impending perforation, existence of calcium plaque, microbe culture result, the size and area of sclera defect, simultaneous application of scleral patch graft, postoperative use of autoserum.
Results: There was no statistical significance in the concomitant application of scleral patch graft (p=0.536) and other risk factors between two groups except scleral defect size (p=0.012). The only significant risk factor was scleral defect size in sub-group analysis which had undergone amniotic transplantation only without scleral patch graft.
Conclusions: Scleral patch graft might not be involved in the risk of re-transplantation, of amniotic membrane, while the size of scleral defect might be the risk factor to predict amniotic membrane re-transplantation after repair of scleromalacia.
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KEYWORD
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Pterygium, Risk factors, Scleral diseases, Transplant
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